Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.76 |
| ▸ | PGR | P06401 | 8/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.76 |
| ▸ | AR | P10275 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 5/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.76 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11783869 | 1.00 | NR3C1 (0.76) | NR3C1PGRCYP3A4ARLMNA | |
| SCHEMBL11647446 | 0.90 | NR3C1 (0.75) | NR3C1PGRCYP3A4ARLMNA | |
| SCHEMBL11245454 | 0.88 | NR3C1 (0.76) | NR3C1PGRCYP3A4ARLMNA | |
| Cyproterone Acetate SCHEMBL11801394 | 0.86 | NR3C1 (1.00) | NR3C1PGRCYP3A4ARLMNA | |
| Cyproterone Acetate SCHEMBL21540064 | 0.86 | NR3C1 (1.00) | NR3C1PGRCYP3A4ARLMNA | |
| Cyproterone Acetate SCHEMBL8021230 | 0.86 | NR3C1 (1.00) | NR3C1PGRCYP3A4ARLMNA | |
| Cyproterone Acetate SCHEMBL9800274 | 0.86 | NR3C1 (1.00) | NR3C1PGRCYP3A4ARLMNA | |
| Cyproterone Acetate SCHEMBL15780914 | 0.86 | NR3C1 (1.00) | NR3C1PGRCYP3A4ARLMNA | |
| Cyproterone Acetate SCHEMBL11795995 | 0.86 | NR3C1 (1.00) | NR3C1PGRCYP3A4ARLMNA | |
| Cyproterone Acetate SCHEMBL5936 | 0.86 | NR3C1 (1.00) | NR3C1PGRCYP3A4ARLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073900-A | DEHALOGENATION, PROGESTATIONAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DT) | 1978-02-14 | — | — | US | disclosed |