Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11592700 | 1.00 | TSHR (0.43) | TSHRCYP2D6CYP2C9KMT2AMEN1 | |
| SCHEMBL11589751 | 0.91 | MEN1 (0.38) | TSHRCYP2D6CYP2C9KMT2AMEN1 | |
| SCHEMBL11589748 | 0.91 | MEN1 (0.38) | TSHRCYP2D6CYP2C9KMT2AMEN1 | |
| SCHEMBL9254326 | 0.82 | CYP2D6 (0.43) | TSHRCYP2D6CYP2C9KMT2AMEN1 | |
| SCHEMBL11592516 | 0.82 | CYP2D6 (0.43) | TSHRCYP2D6CYP2C9KMT2AMEN1 | |
| SCHEMBL9254318 | 0.82 | CYP2D6 (0.43) | TSHRCYP2D6CYP2C9KMT2AMEN1 | |
| SCHEMBL9254313 | 0.82 | CYP2D6 (0.43) | TSHRCYP2D6CYP2C9KMT2AMEN1 | |
| SCHEMBL11591849 | 0.82 | PABPC1 (0.41) | TSHRCYP2D6CYP2C9KMT2AMEN1 | |
| SCHEMBL11591845 | 0.82 | PABPC1 (0.41) | TSHRCYP2D6CYP2C9KMT2AMEN1 | |
| SCHEMBL11593227 | 0.81 | MEN1 (0.43) | TSHRCYP2D6CYP2C9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073942-A | Halo-substituted hydroxybenzyl-amines as secretolytic agents | BOEHRINGER INGELHEIM GMBH (DT) | 1978-02-14 | — | — | US | disclosed |