Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938764 | 0.79 | SMN1; SMN2 (0.53) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18767163 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8241614 | 0.76 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29399627 | 0.76 | MEN1 (0.65) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL35185 | 0.76 | MEN1 (0.65) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8092422 | 0.75 | CA9 (0.68) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1421294 | 0.75 | SMN1; SMN2 (0.68) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| Trimethylammonium SCHEMBL4399445 | 0.74 | KMT2A (0.50) | ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL11311538 | 0.74 | CYP2C19 (0.49) | ALDH1A1LMNAKMT2A | |
| Isophthalic Acid SCHEMBL21683231 | 0.73 | KMT2A (0.58) | PLA2G4BKMT2ANR1H4PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161531-A | Diuretic and saluretic 5-sulfamoylbenzoic acid derivatives carrying a heterocyclic substituent | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-17 | — | — | US | disclosed |
| US-4118397-A | DIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |
| US-4111953-A | DIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |
| US-4093735-A | DIURETICS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-06-06 | — | — | US | disclosed |
| US-4010273-A | DIURETICS, SALURETICS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-01 | — | — | US | disclosed |