Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 10/20 | 0.74 |
| ▸ | DYRK1B | Q9Y463 | 9/20 | 0.73 |
| ▸ | CLK1 | P49759 | 8/20 | 0.73 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.63 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338532 | 0.88 | DYRK1A (0.76) | DYRK1ADYRK1BCLK1HSD17B1BCL2L1 | |
| SCHEMBL13045530 | 0.86 | DYRK1A (0.73) | DYRK1ADYRK1BCLK1HSD17B1BCL2L1 | |
| SCHEMBL23041064 | 0.85 | DYRK1A (0.63) | DYRK1ADYRK1BCLK1HSD17B1BCL2L1 | |
| SCHEMBL23041057 | 0.85 | DYRK1A (0.63) | DYRK1ADYRK1BCLK1HSD17B1BCL2L1 | |
| SCHEMBL23041055 | 0.85 | DYRK1A (0.63) | DYRK1ADYRK1BCLK1HSD17B1BCL2L1 | |
| SCHEMBL23041062 | 0.85 | DYRK1A (0.63) | DYRK1ADYRK1BCLK1HSD17B1BCL2L1 | |
| SCHEMBL6321234 | 0.84 | BCL2L1 (0.74) | DYRK1ADYRK1BCLK1HSD17B1BCL2L1 | |
| SCHEMBL31356465 | 0.84 | BCL2L1 (0.74) | DYRK1ADYRK1BCLK1HSD17B1BCL2L1 | |
| SCHEMBL28260363 | 0.83 | DYRK1A (0.69) | DYRK1ADYRK1BCLK1HSD17B1BCL2L1 | |
| SCHEMBL20748215 | 0.82 | HSD17B1 (0.80) | DYRK1ADYRK1BCLK1HSD17B1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |