Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11656969 | 0.79 | PARP10 (0.50) | DYRK1ATNKS2PARP2PTGS2NPC1 | |
| SCHEMBL11651025 | 0.76 | PARP15 (0.50) | ALDH1A1KDM4EL3MBTL1TNKS2PARP2 | |
| SCHEMBL11652246 | 0.74 | PARP15 (0.43) | ALDH1A1KDM4EL3MBTL1TNKS2PARP2 | |
| SCHEMBL11649328 | 0.73 | PTGS2 (0.35) | ALDH1A1L3MBTL1TNKS2PARP2PTGS2 | |
| SCHEMBL11649318 | 0.73 | PTGS2 (0.39) | TNKS2PARP2PTGS2LMNASMN1; SMN2 | |
| SCHEMBL11651246 | 0.72 | PARP15 (0.54) | ALDH1A1KDM4ETNKS2PARP2NPC1 | |
| SCHEMBL11652101 | 0.71 | CASR (0.34) | ALDH1A1KDM4EL3MBTL1TNKS2PARP2 | |
| SCHEMBL11651408 | 0.71 | TDP1 (0.37) | L3MBTL1TNKS2PARP2PTGS2TP53 | |
| SCHEMBL11653522 | 0.69 | TP53 (0.39) | ALDH1A1KDM4ETNKS2PARP2PTGS2 | |
| SCHEMBL8402940 | 0.69 | TNKS2 (0.51) | ALDH1A1KDM4EL3MBTL1CHEK1PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075218-A | INSECTICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-3974286-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1976-08-10 | — | — | US | disclosed |