Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645369 | 0.88 | SMN1; SMN2 (0.41) | MAPTSMN1; SMN2NPSR1HTTALDH1A1 | |
| SCHEMBL11647431 | 0.86 | MAPT (0.43) | MAPTSMN1; SMN2NPSR1HTTALDH1A1 | |
| SCHEMBL11643855 | 0.83 | ALDH1A1 (0.54) | MAPTSMN1; SMN2NPSR1HTTALDH1A1 | |
| SCHEMBL11646781 | 0.83 | MAPT (0.72) | MAPTSMN1; SMN2NPSR1HTTALDH1A1 | |
| SCHEMBL11647437 | 0.81 | ALDH1A1 (0.49) | MAPTSMN1; SMN2NPSR1HTTALDH1A1 | |
| SCHEMBL11646762 | 0.77 | MAPKAPK2 (0.47) | MAPTSMN1; SMN2NPSR1HTTALDH1A1 | |
| SCHEMBL11643864 | 0.74 | ALDH1A1 (0.70) | MAPTSMN1; SMN2NPSR1HTTALDH1A1 | |
| SCHEMBL26131318 | 0.74 | MAPT (0.47) | MAPTSMN1; SMN2HTTALDH1A1L3MBTL1 | |
| SCHEMBL26128688 | 0.69 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2HTTALDH1A1L3MBTL1 | |
| SCHEMBL10465057 | 0.69 | MAPT (0.69) | MAPTSMN1; SMN2NPSR1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112100-A | INCREASING THE ENDOGENOUS PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |