Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | PGR | P06401 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.55 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11649809 | 1.00 | LMNA (0.62) | LMNASMN1; SMN2NR3C1HIF1ACYP3A4 | |
| SCHEMBL11649806 | 1.00 | LMNA (0.62) | LMNASMN1; SMN2NR3C1HIF1ACYP3A4 | |
| SCHEMBL11322772 | 0.90 | LMNA (0.58) | LMNASMN1; SMN2NR3C1HIF1ACYP3A4 | |
| SCHEMBL11322766 | 0.90 | LMNA (0.58) | LMNASMN1; SMN2NR3C1HIF1ACYP3A4 | |
| SCHEMBL11407501 | 0.89 | LMNA (0.64) | LMNASMN1; SMN2NR3C1HIF1ACYP3A4 | |
| SCHEMBL11407499 | 0.89 | LMNA (0.64) | LMNASMN1; SMN2NR3C1HIF1ACYP3A4 | |
| SCHEMBL11407496 | 0.89 | LMNA (0.64) | LMNASMN1; SMN2NR3C1HIF1ACYP3A4 | |
| SCHEMBL11834766 | 0.88 | LMNA (0.63) | LMNASMN1; SMN2NR3C1HIF1ACYP3A4 | |
| SCHEMBL11525689 | 0.88 | LMNA (0.63) | LMNASMN1; SMN2NR3C1HIF1ACYP3A4 | |
| SCHEMBL11525694 | 0.88 | LMNA (0.63) | LMNASMN1; SMN2NR3C1HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4113722-A | Steroidal[16α,17-b]benzodioxins | E. R. SQUIBB & SONS, INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-3976638-A | STEROID, ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-08-24 | — | — | US | disclosed |