⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3899901 | 0.72 | — | — | |
| SCHEMBL2378319 | 0.69 | — | — | |
| SCHEMBL27913833 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL3890570 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL5049308 | 0.67 | — | — | |
| SCHEMBL50777 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL10782213 | 0.65 | — | — | |
| SCHEMBL4305172 | 0.65 | — | — | |
| Fluoride SCHEMBL23120036 | 0.64 | ALDH1A1 (0.30) | — | |
| SCHEMBL96260 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105985458-B | Silica gel/clay composite carrier, chromium catalyst, preparation method and application thereof | 中国石油天然气股份有限公司 | 2018-12-25 | — | — | CN | claimed |
| CN-105985458-A | Silica gel/clay composite carrier, chromium catalyst, preparation method and application thereof | 中国石油天然气股份有限公司 | 2016-10-05 | — | — | CN | claimed |
| US-8846915-B2 | Process for the manufacture of rosuvastatin calcium using crystalline rosuvastatin ethyl ester | AUROBINDO PHARMA LTD. (IN) | 2014-09-30 | — | — | US | claimed |
| US-8759518-B2 | Intermediates for the preparation of HMG CoA reductase inhibitors and processes for the preparation thereof | CADILA HEALTHCARE LIMITED (IN) | 2014-06-24 | — | — | US | claimed |
| US-20130158263-A1 | INTERMEDIATES FOR THE PREPARATION OF HMG COA REDUCTASE INHIBITORS AND PROCESSES FOR THE PREPARATION THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2013-06-20 | — | — | US | claimed |
| US-8212035-B2 | Process for preparation of rosuvastatin calcium field of the invention | AUROBINDO PHARMA LTD. (IN) | 2012-07-03 | — | — | US | claimed |
| EP-2467363-A1 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER | Aurobindo Pharma Limited (IN) | 2012-06-27 | — | — | EP | claimed |
| US-20120149905-A1 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER | AUROBINDO PHARMA LTD (IN) | 2012-06-14 | — | — | US | claimed |
| WO-2011104725-A2 | HMG-COA REDUCTASE INHIBITORS AND PROCESS FOR THE PREPARATION THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2011-09-01 | — | — | WO | claimed |
| WO-2011021058-A1 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER | AUROBINDO PHARMA LIMITED (IN) | 2011-02-24 | — | — | WO | claimed |
| US-20090312547-A1 | PROCESS FOR PREPARATION OF ROSUVASTATIN CALCIUM FIELD OF THE INVENTION | AUROBINDO PHARMA LTD (IN) | 2009-12-17 | — | — | US | claimed |
| EP-2125754-A1 | AN IMPROVED PROCESS FOR PREPARATION OF ROSUVASTATIN CALCIUM | Aurobindo Pharma Limited (IN) | 2009-12-02 | — | — | EP | claimed |
| WO-2009118598-A1 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM WITH HIGH PURITY | AUROBINDO PHARMA LIMITED (IN) | 2009-10-01 | — | — | WO | claimed |
| WO-2008096257-A1 | AN IMPROVED PROCESS FOR PREPARATION OF ROSUVASTATIN CALCIUM | AUROBINDO PHARMA LIMITED (IN) | 2008-08-14 | — | — | WO | claimed |
| US-7091290-B2 | Method for preparing homo-and co-polymers of cyclic olefin compounds using an organic boron compound as a catalyst activator | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2006-08-15 | — | — | US | claimed |
| US-20050245703-A1 | addition polymerization of nonaromatic cyclic olefins, such as alkylnorbornenes and dicyclopentadienes, in the presence of a catalyst complex also including a nickel II carboxylate and an aluminoxane compound; high molecular weight polymer in high yields; gelation inhibition | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2005-11-03 | — | — | US | claimed |
| US-5218138-A | Forming a complex with dialkylated borane and reducing the complex | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1993-06-08 | — | — | US | claimed |
| US-12582745-B2 | Adhesive composition for hard tissue repair | JIAXING JINGYIN BIOTECHNOLOGY CO., LTD (CN) | 2026-03-24 | — | — | US | disclosed |
| US-4824959-A | Intermediates for antihypercholesterolemic tetrazole compounds | BRISTOL-MYERS COMPANY (US) | 1989-04-25 | — | — | US | disclosed |
| WO-1988006584-A1 | ANTIHYPERCHOLESTEROLEMIC TETRAZOLE COMPOUNDS | BRISTOL-MYERS COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |