Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18381234 | 0.96 | SHBG (0.46) | SHBG | |
| SCHEMBL22088568 | 0.86 | SHBG (0.37) | SHBG | |
| SCHEMBL11787039 | 0.85 | SHBG (0.49) | SHBG | |
| SCHEMBL8475737 | 0.77 | SHBG (0.31) | SHBG | |
| SCHEMBL15963496 | 0.77 | SHBG (0.51) | SHBG | |
| SCHEMBL15903885 | 0.77 | SHBG (0.51) | SHBG | |
| SCHEMBL9806329 | 0.75 | SHBG (0.43) | SHBG | |
| SCHEMBL11224788 | 0.75 | SHBG (0.43) | SHBG | |
| SCHEMBL9806327 | 0.75 | SHBG (0.43) | SHBG | |
| SCHEMBL9806286 | 0.75 | SHBG (0.43) | SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105676-A | 2-ALKOXY ETHYL-6-/3-CYANOPROPYL/TETRAHYDROPYRAN-2-OL | HOFFMANN-LA ROCHE INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4044004-A | Total steroid synthesis employing substituted isoxazole derivatives | HOFFMANN-LA ROCHE INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3994930-A | MULTISTEP, STEREOSPECIFIC TOTAL SYNTHESIS OF STEROIDS | HOFFMANN-LA ROCHE INC. (US) | 1976-11-30 | — | — | US | disclosed |
| US-3972896-A | Aryl ketals of polycyclic oxo compounds and processes | HOFFMANN-LA ROCHE INC. (US) | 1976-08-03 | — | — | US | disclosed |
| US-3965138-A | Steroid total synthesis process utilizing a cyanoalkyl A-ring precursor | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3960896-A | Aryl ketals of polycyclic oxo compounds and processes | HOFFMANN-LA ROCHE INC. (US) | 1976-06-01 | — | — | US | disclosed |
| US-3950358-A | ARYL KETALS OF 3,7-DIHYDROXY-11-OXO-DODEC-1-ENE | HOFFMANN-LA ROCHE INC. (US) | 1976-04-13 | — | — | US | disclosed |
| US-3948951-A | Aryl ketals of 1-chloro-4-oxo-pentane | HOFFMANN-LA ROCHE INC. (US) | 1976-04-06 | — | — | US | disclosed |