Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27393358 | 0.82 | KIF11 (0.50) | KCNN4ALDH1A1TAAR1KIF11KMT2A | |
| SCHEMBL11773264 | 0.78 | KCNN4 (0.55) | KCNN4TSHRALDH1A1TAAR1CYP1A2 | |
| SCHEMBL9388513 | 0.74 | KCNN4 (0.50) | KCNN4TSHRALDH1A1TAAR1CYP1A2 | |
| SCHEMBL9092262 | 0.74 | KCNN4 (0.50) | KCNN4TSHRALDH1A1TAAR1CYP1A2 | |
| SCHEMBL6379499 | 0.74 | KCNN4 (0.50) | KCNN4TSHRALDH1A1TAAR1CYP1A2 | |
| SCHEMBL30209488 | 0.73 | KCNN4 (0.44) | KCNN4TSHRALDH1A1TAAR1CYP1A2 | |
| SCHEMBL8904915 | 0.72 | TSHR (0.48) | KCNN4TSHRALDH1A1TAAR1CYP1A2 | |
| SCHEMBL10804256 | 0.72 | TSHR (0.48) | KCNN4TSHRALDH1A1TAAR1CYP1A2 | |
| SCHEMBL7194334 | 0.72 | TSHR (0.48) | KCNN4TSHRALDH1A1TAAR1CYP1A2 | |
| SCHEMBL3849013 | 0.70 | TSHR (0.46) | KCNN4TSHRALDH1A1TAAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108836-A | Process for synthesizing acetylene-substituted polyimides and polyimides thereof | HUGHES AIRCRAFT COMPANY (US) | 1978-08-22 | — | — | US | disclosed |