SCHEMBL1165189

SCHEMBL1165189

O=C(O)C1=C(O)CCCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 3/20 0.33
NPSR1 Q6W5P4 1/20 0.33
DHODH Q02127 1/20 0.32
TRIM24 O15164 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
KDM4E B2RXH2 1/20 0.31
NSD2 O96028 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
APEX1 P27695 1/20 0.31
RECQL P46063 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10363649 0.94
SCHEMBL8781919 0.82
SCHEMBL217840 0.82 DHODH (0.41) HCAR2TSHRALDH1A1NPSR1DHODH
SCHEMBL12491707 0.82 DHODH (0.41) HCAR2TSHRALDH1A1NPSR1DHODH
SCHEMBL5415654 0.82 DHODH (0.41) HCAR2TSHRALDH1A1NPSR1DHODH
SCHEMBL17024327 0.82 DHODH (0.41) HCAR2TSHRALDH1A1NPSR1DHODH
SCHEMBL12491709 0.82 DHODH (0.41) HCAR2TSHRALDH1A1NPSR1DHODH
SCHEMBL17024326 0.82 DHODH (0.41) HCAR2TSHRALDH1A1NPSR1DHODH
SCHEMBL28247062 0.82 DHODH (0.41) HCAR2TSHRALDH1A1NPSR1DHODH
SCHEMBL29008433 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60008252-A None JP disclosed
US-12603275-B2 Electrochemical cells comprising coated cathode active material and silyl ester phosphonate as electrolyte additive BASF SE (DE) 2026-04-14 US disclosed
CN-111480257-B Comprising oligosilylphosphines electrolyte composition of acid ester 巴斯夫欧洲公司 2025-05-02 CN disclosed
CN-110915052-B Heterocyclic sulfonyl fluoride additives for electrolyte compositions of lithium batteries 巴斯夫欧洲公司 2024-04-23 CN disclosed
US-11936002-B2 Electrolyte composition comprising oligomeric silyl ester phosphonates BASF SE (DE) 2024-03-19 US disclosed
EP-4308573-A1 CYCLIC COMPOUNDS AND METHODS OF USING SAME Schrödinger, Inc. (US) 2024-01-24 EP disclosed
CN-109716578-B Electrochemical cell comprising difunctional silyl phosphonate 巴斯夫欧洲公司 2023-05-16 CN disclosed
EP-3724943-B1 ELECTROLYTE COMPOSITION COMPRISING OLIGOMERIC SILYL ESTER PHOSPHONATES BASF SE (DE) 2023-05-10 EP disclosed
CN-110249466-B Functionalized sulfonyl fluoride additives for electrolyte compositions for lithium ion batteries 巴斯夫欧洲公司 2023-03-21 CN disclosed
US-11444326-B2 Heterocyclic sulfonyl fluoride additives for electrolyte composition for lithium batteries BASF SE (DE) 2022-09-13 US disclosed
EP-2768064-A1 Use of substituted alkynyl sulfonates, carbonates and oxalates as additives in electrolytes of secondary lithium-ion batteries BASF SE (DE) 2014-08-20 EP disclosed
US-20140193707-A1 SULFUR-CONTAINING ADDITIVES FOR ELECTROCHEMICAL OR OPTOELECTRONIC DEVICES BASF SE (DE) 2014-07-10 US disclosed
WO-2014095407-A1 USE OF FLUOROISOPROPYL DERIVATIVES AS ADDITIVES IN ELECTROLYTES BASF SE (DE) 2014-06-26 WO disclosed
WO-2014083113-A1 CRYSTALLIZATION PROCESS OF TRICYCLIC INDOLE DERIVATIVES GE HEALTHCARE LIMITED (GB) 2014-06-05 WO disclosed
WO-2011021036-A1 POLYKETIDES ANALOGUES AND METHODS FOR THEIR PRODUCTION BIOTICA TECHNOLOGY LIMITED (GB) 2011-02-24 WO disclosed
US-20110039808-A1 Multitarget Compounds Active at a PPAR and Cannabinoid Receptor NOGRA PHARMA LIMITED (IE) 2011-02-17 US disclosed
EP-2222287-A2 MULTITARGET COMPOUNDS ACTIVE AT A PPAR AND CANNABINOID RECEPTOR Giuliani International Limited (IE) 2010-09-01 EP disclosed
WO-2009080821-A2 RECEPTOR TARGETING LIGANDS GIULIANI INTERNATIONAL LIMITED (IE) 2009-07-02 WO disclosed
US-5180418-A HERBICIDALLY ACTIVE THIADIAZABICYCLONONANES AND NONENES CIBA-GEIGY CORPORATION (US) 1993-01-19 US disclosed
JP-S608252-A SALICYLIC ACID DERIVATIVE AND HERBICIDE SHOWA DENKO KK 1985-01-17 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12603275-B2 Electrochemical cells comprising coated cathode active material and silyl ester phosphonate as electrolyte additive ILK, ITGB7, ITGAL HCAR2 4856/4885TSHR 3625/4885ALDH1A1 3369/4885
US-20110039808-A1 Multitarget Compounds Active at a PPAR and Cannabinoid Receptor PPARA, PPARG, PPARD HCAR2 9/4885TSHR 586/4885ALDH1A1 899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.