Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.51 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485325 | 0.81 | KMT2A (0.59) | MAPTLMNASMN1; SMN2NQO2NQO1 | |
| SCHEMBL1957465 | 0.80 | GCGR (0.48) | ABCB1MAPTSMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL1957467 | 0.80 | GCGR (0.48) | ABCB1MAPTSMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL5613888 | 0.79 | KDM4E (0.49) | ABCB1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL5613889 | 0.79 | KDM4E (0.49) | ABCB1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL9097324 | 0.78 | POLB (0.49) | LMNASMN1; SMN2NQO2NQO1L3MBTL1 | |
| SCHEMBL9097327 | 0.78 | POLB (0.49) | LMNASMN1; SMN2NQO2NQO1L3MBTL1 | |
| SCHEMBL1388608 | 0.78 | NQO2 (0.49) | CAPN1CTSLCTSBMAPTLMNA | |
| SCHEMBL1388607 | 0.78 | NQO2 (0.49) | CAPN1CTSLCTSBMAPTLMNA | |
| SCHEMBL1959686 | 0.78 | PDE4B (0.46) | ABCB1MAPTSMN1; SMN2THRBTUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082721-A | 1,4-BIS(1-CYANO-CARBOCYCLIC-UNSATURATER HYDROCARBYL) DYE COMPOSITIONS | U.S. PHILIPS CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |