Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11651933 | 0.79 | KDM4E (0.46) | KDM4ECYP1A2CYP3A4HDAC3HDAC4 | |
| SCHEMBL11653068 | 0.79 | KDM4E (0.52) | HPGDKDM4ERAB9AL3MBTL1HDAC3 | |
| SCHEMBL11652981 | 0.79 | KDM4E (0.52) | HPGDKDM4ERAB9AL3MBTL1HDAC3 | |
| SCHEMBL11652714 | 0.79 | KDM4E (0.52) | HPGDKDM4ERAB9AL3MBTL1HDAC3 | |
| SCHEMBL11652618 | 0.79 | KDM4E (0.52) | HPGDKDM4ERAB9AL3MBTL1HDAC3 | |
| SCHEMBL11652486 | 0.79 | KDM4E (0.52) | HPGDKDM4ERAB9AL3MBTL1HDAC3 | |
| SCHEMBL22207107 | 0.78 | FPR2 (0.50) | RECQLHPGDKDM4EALDH1A1NPC1 | |
| SCHEMBL27821876 | 0.77 | HCAR2 (0.45) | RECQLHPGDKDM4EABL1CYP1A2 | |
| SCHEMBL11649853 | 0.77 | KDM4E (0.53) | KDM4EHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11648634 | 0.77 | GAA (0.47) | KDM4EHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4089865-A | Certain thiazole compounds | SYNTEX (U.S.A.) INC. (US) | 1978-05-16 | — | — | US | disclosed |
| US-4001421-A | THIAZOLE CARDIOVASCULAR AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-01-04 | — | — | US | disclosed |