Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 5/20 | 1.00 |
| ▸ | PRKCG | P05129 | 5/20 | 1.00 |
| ▸ | PRKCB | P05771 | 5/20 | 1.00 |
| ▸ | PRKCA | P17252 | 5/20 | 1.00 |
| ▸ | PRKCH | P24723 | 5/20 | 1.00 |
| ▸ | PRKCI | P41743 | 5/20 | 1.00 |
| ▸ | PRKCE | Q02156 | 5/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 5/20 | 1.00 |
| ▸ | PRKCZ | Q05513 | 5/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 5/20 | 1.00 |
| ▸ | PRKD1 | Q15139 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | PRKACA | P17612 | 4/20 | 0.70 |
| ▸ | PRKACG | P22612 | 4/20 | 0.70 |
| ▸ | PRKACB | P22694 | 4/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084457 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL20553518 | 0.99 | PRKD3 (0.98) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL1321843 | 0.99 | PRKD3 (0.98) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL2457955 | 0.93 | PRKD3 (0.87) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL18599911 | 0.93 | PRKD3 (0.87) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL23951537 | 0.89 | PRKD3 (0.81) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL9016187 | 0.87 | PRKD3 (0.77) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL10982199 | 0.87 | PRKD3 (0.77) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL10988093 | 0.87 | PRKD3 (0.77) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL2456661 | 0.85 | PRKD3 (0.74) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913932-B2 | Maturation of mammalian hepatocytes | TAKARA BIO EUROPE AB (SE) | 2021-02-09 | — | — | US | claimed |
| US-9006394-B2 | Peptide-presenting surfaces for long-term culture of pluripotent cells | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-04-14 | — | — | US | claimed |
| US-20140287505-A1 | PEPTIDE-PRESENTING SURFACES FOR LONG-TERM CULTURE OF PLURIPOTENT CELLS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2014-09-25 | — | — | US | claimed |
| US-8648170-B2 | Peptide-presenting surfaces for long-term culture of pluripotent cells | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-02-11 | — | — | US | claimed |
| EP-1479386-A1 | Use of isoquinoline-derivatives for treating and preventing pigmentary disorders | Switch Biotech Aktiengesellschaft (DE) | 2004-11-24 | — | — | EP | claimed |
| US-12529032-B2 | Methods and culture substrates for controlled induction of biomimetic neural tissues comprising singular rosette structures | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250346858-A1 | METHODS OF GENERATING THREE-DIMENSIONAL RETINAL ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS | UNIV INDIANA TRUSTEES (US) | 2025-11-13 | — | — | US | disclosed |
| US-20250207101-A1 | NEXT GENERATION DESIGNER LIVER ORGANOIDS AND THEIR METHODS OF PREPARATION AND USE | UNIV ARIZONA STATE (US) | 2025-06-26 | — | — | US | disclosed |
| WO-2025094630-A1 | METHOD FOR PRODUCING THREE-DIMENSIONAL SKIN TISSUE, AND THREE-DIMENSIONAL SKIN TISSUE | ポーラ化成工業株式会社 | 2025-05-08 | — | — | WO | disclosed |
| US-12275957-B2 | Next generation designer liver organoids and their methods of preparation and use | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2025-04-15 | — | — | US | disclosed |
| US-20250034523-A1 | METHODS OF GENERATING HUMAN COCHLEAR HAIR CELLS | THE TRUSTEES OF INDIANA UNIVERSITY | 2025-01-30 | — | — | US | disclosed |
| US-20240335593-A1 | GENERATING ALLOGENIC ENDOTHELIAL CELL-SEEDED VASCULAR GRAFTS AND METHODS OF USE THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2024-10-10 | — | — | US | disclosed |
| CN-1233188-A | Medicines comprising Rho kinase inhibitor | YOSHITOMI PHARMACEUTICAL (JP) | 1999-10-27 | — | — | CN | disclosed |
| US-5747507-A | MYOCARDIAL DISEASE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1998-05-05 | — | — | US | disclosed |
| EP-0654266-A1 | CARDIAC PROTECTIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-05-24 | — | — | EP | disclosed |
| US-4560755-A | VASODILATOR, HYPOTENSOR | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-12-24 | — | — | US | disclosed |
| US-4525589-A | Isoquinolinesulfonyl derivatives | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-06-25 | — | — | US | disclosed |
| EP-0061673-B1 | ISOQUINOLINESULFONYL DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-10-24 | — | — | EP | disclosed |
| US-4456757-A | MUSCLE RELAXANTS, VASODILATORS, HYPOTENSIVE AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-06-26 | — | — | US | disclosed |
| EP-0061673-A1 | Isoquinolinesulfonyl derivatives and process for the preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529032-B2 | Methods and culture substrates for controlled induction of biomimetic neural tissues comprising singular rosette structures | NES, CDH1, SHH | PRKD3 774/4885PRKCG 430/4885PRKCB 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.