Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.48 |
| ▸ | CDK1 | P06493 | 2/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11653533 | 0.81 | KDM4E (0.60) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL28280284 | 0.81 | KMT2A (0.41) | NPC1RAB9AMAPTCCNB2CDK1 | |
| SCHEMBL10936827 | 0.80 | NPC1 (0.47) | KDM4ENPC1RAB9AMAPTCCNB2 | |
| SCHEMBL11657634 | 0.78 | KDM4E (0.53) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL11651810 | 0.76 | KDM4E (0.67) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL24108255 | 0.75 | KDM4E (0.53) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL30411878 | 0.75 | KDM4E (0.53) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL11659214 | 0.73 | KDM4E (0.67) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL4769329 | 0.72 | KDM4E (0.59) | KDM4ENPC1RAB9AMAPTCASP3 | |
| SCHEMBL7945775 | 0.70 | KDM4E (0.73) | KDM4ENPC1RAB9AMAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4113736-A | NONTOXIC POLYMER STABILIZERS | S. A. LABAZ (BE) | 1978-09-12 | — | — | US | disclosed |