Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11656559 | 0.91 | TSHR (0.48) | L3MBTL1TDP1 | |
| SCHEMBL11657549 | 0.90 | NPC1 (0.40) | SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL11670228 | 0.90 | ABCB1 (0.46) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11656949 | 0.90 | TBXA2R (0.38) | SMN1; SMN2HPGDKMT2AL3MBTL1 | |
| SCHEMBL11656355 | 0.90 | MAPK1 (0.51) | SMN1; SMN2HPGDL3MBTL1TDP1 | |
| SCHEMBL11657750 | 0.90 | TBXA2R (0.48) | SMN1; SMN2HPGD | |
| SCHEMBL11659488 | 0.90 | HPGD (0.37) | SMN1; SMN2HPGDL3MBTL1TDP1 | |
| SCHEMBL11657383 | 0.89 | TBXA2R (0.47) | SMN1; SMN2HPGDADRB2ADRB1KMT2A | |
| SCHEMBL11661605 | 0.88 | HIF1A (0.37) | SMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL11655520 | 0.88 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4020177-A | CONTRACEPTIVES | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |