Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659488 | 0.90 | HPGD (0.37) | SMN1; SMN2 | |
| SCHEMBL11654437 | 0.90 | SMN1; SMN2 (0.46) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11656559 | 0.89 | TSHR (0.48) | — | |
| SCHEMBL11656949 | 0.88 | TBXA2R (0.38) | KMT2ASMN1; SMN2 | |
| SCHEMBL11657549 | 0.88 | NPC1 (0.40) | SMN1; SMN2 | |
| SCHEMBL11657750 | 0.88 | TBXA2R (0.48) | SMN1; SMN2 | |
| SCHEMBL11656355 | 0.88 | MAPK1 (0.51) | SMN1; SMN2 | |
| SCHEMBL11662117 | 0.88 | ABCB1 (0.49) | ABCB1KMT2AMEN1TAAR1MAOB | |
| SCHEMBL11661605 | 0.87 | HIF1A (0.37) | SMN1; SMN2 | |
| SCHEMBL11655520 | 0.86 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4020177-A | CONTRACEPTIVES | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |