Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.61 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69025 | 0.88 | PTPN11 (0.68) | PLAUPTPN11LCKCA1CA2 | |
| SCHEMBL29365729 | 0.88 | PTPN11 (0.68) | PLAUPTPN11LCKCA1CA2 | |
| SCHEMBL8732524 | 0.86 | PTPN11 (0.66) | PLAUPTPN11LCKCA1CA2 | |
| SCHEMBL17829703 | 0.85 | PTPN11 (0.57) | PLAUPTPN11LCKCA1CA2 | |
| SCHEMBL9979782 | 0.84 | PTPN11 (0.64) | PLAUPTPN11LCKCA1CA2 | |
| SCHEMBL4498737 | 0.83 | PTPN11 (0.58) | PLAUPTPN11LCKCA1CA2 | |
| SCHEMBL30362293 | 0.83 | PTPN11 (0.58) | PLAUPTPN11LCKCA1CA2 | |
| SCHEMBL709231 | 0.82 | LCK (0.62) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL1003761 | 0.81 | KDM4E (0.62) | PLAUPTPN11LCKCA1CA2 | |
| SCHEMBL264052 | 0.81 | PTPN11 (0.60) | PLAUPTPN11LCKCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103667202-B | N ε-(1-methyl ring third-2-alkene acid amides)-Methionin translation system and application thereof | INSTITUTE OF BIOPHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2016-01-13 | — | — | CN | disclosed |
| CN-103667202-A | N<epsilon>-(1-methylcyclopropyl-2-acrylamide)-lysine translation system and application thereof | INST BIOPHYSICS CN ACAD SCI | 2014-03-26 | — | — | CN | disclosed |
| US-4107329-A | Fluorinated compounds as therapeutics | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-08-15 | — | — | US | disclosed |