Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.64 |
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | XDH | P47989 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365729 | 0.96 | PTPN11 (0.68) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL69025 | 0.96 | PTPN11 (0.68) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL18288017 | 0.94 | ALOX15 (0.58) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL10900668 | 0.94 | ALOX15 (0.58) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL30572104 | 0.94 | ALOX15 (0.58) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL709231 | 0.93 | LCK (0.62) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL8732524 | 0.93 | PTPN11 (0.66) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL23692611 | 0.90 | CA1 (0.69) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL811009 | 0.90 | PTPN11 (0.58) | PTPN11LCKCA1CA2CA12 | |
| SCHEMBL30151494 | 0.90 | PTPN11 (0.58) | PTPN11LCKCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331604-B1 | POLYESTER MELT-PHASE COMPOSITIONS HAVING IMPROVED THERMO-OXIDATIVE STABILITY, AND METHODS OF MAKING AND USING THEM | GRUPO PETROTEMEX SA DE CV (MX) | 2017-12-27 | — | — | EP | claimed |
| US-9978474-B2 | Conductive open frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-22 | — | — | US | disclosed |
| US-9978474-B2 | Conductive open frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-22 | — | — | US | disclosed |
| US-20160247593-A1 | CONDUCTIVE OPEN FRAMEWORKS | UNITED STATES DEPARTMENT OF ENERGY | 2016-08-25 | — | — | US | disclosed |
| US-20160247593-A1 | CONDUCTIVE OPEN FRAMEWORKS | UNITED STATES DEPARTMENT OF ENERGY | 2016-08-25 | — | — | US | disclosed |
| US-9269473-B2 | Conductive open frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-23 | — | — | US | disclosed |
| US-9269473-B2 | Conductive open frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-23 | — | — | US | disclosed |
| US-20140081014-A1 | CONDUCTIVE OPEN FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-20 | — | — | US | disclosed |
| WO-2012082213-A2 | CONDUCTIVE OPEN FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160247593-A1 | CONDUCTIVE OPEN FRAMEWORKS | GJB2, OR10J3, EPCAM | PTPN11 2439/4885LCK 474/4885CA1 1801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.