Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11656997 | 0.88 | MAPT (0.60) | MAPTALDH1A1LMNAAPEX1NPC1 | |
| SCHEMBL11656106 | 0.87 | MAPT (0.51) | MAPTALDH1A1LMNAAPEX1NPC1 | |
| SCHEMBL9469134 | 0.87 | MAPT (0.51) | MAPTALDH1A1LMNAAPEX1NPC1 | |
| SCHEMBL16266288 | 0.84 | MAPT (0.53) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL11652493 | 0.83 | CA1 (0.56) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL3897182 | 0.81 | MAPT (0.61) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL11650208 | 0.81 | GAA (0.48) | MAPTALDH1A1LMNANPC1SMN1; SMN2 | |
| SCHEMBL31213402 | 0.76 | MAPT (0.63) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL8138395 | 0.75 | MAPT (0.51) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL8138399 | 0.75 | MAPT (0.51) | MAPTALDH1A1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096112-A | POLYVINYL CHLORIDE | LABAZ (FR) | 1978-06-20 | — | — | US | disclosed |
| US-4024155-A | 2-(3'-Methoxy-4'-hydroxy-phenol)-indole | LABAZ (FR) | 1977-05-17 | — | — | US | disclosed |