Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31213402 | 0.95 | MAPT (0.63) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL29420484 | 0.86 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL23817280 | 0.82 | NPC1 (0.57) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL934433 | 0.81 | GAA (0.61) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11655166 | 0.81 | MAPT (0.52) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11656997 | 0.81 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL935280 | 0.80 | CTSL (0.56) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8138399 | 0.80 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL8138395 | 0.80 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL11656106 | 0.80 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557248-B2 | Method of forming a carbon-heteroatom bond | RHODIA CHIMIE (FR) | 2009-07-07 | — | — | US | claimed |
| US-20070243999-A1 | Method of Forming a Carbon-Heteroatom Bond | RHODIA CHIMIE (FR) | 2007-10-18 | — | — | US | claimed |
| CN-114195676-B | Biarylhydrazine compound and adduct thereof and application of compound in preparation of antitumor drugs | 广州药本君安医药科技股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114195676-A | Biarylhydrazine compound and adduct thereof and application of compound in preparation of antitumor drugs | 广州药本君安医药科技股份有限公司 | 2022-03-18 | — | — | CN | disclosed |