Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25948638 | 0.89 | — | — | |
| SCHEMBL25333046 | 0.89 | — | — | |
| SCHEMBL6642798 | 0.86 | NPSR1 (0.30) | — | |
| SCHEMBL7171116 | 0.85 | NPSR1 (0.46) | ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL9267120 | 0.85 | NPSR1 (0.46) | ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL7171118 | 0.85 | NPSR1 (0.46) | ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL11650881 | 0.85 | ADRA1A (0.34) | — | |
| SCHEMBL2335326 | 0.84 | NPSR1 (0.35) | ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL18936288 | 0.84 | — | — | |
| SCHEMBL17164585 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110214136-A | Pyrazole derivatives as MALT1 inhibitor | 詹森药业有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-106170489-B | New Pyrazolopyrimidine derivative and its purposes as MALT1 inhibitor | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-109071545-A | New Pyrazolopyrimidine derivative | 拜耳动物保健有限责任公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108473499-A | Novel Pyrazolopyrimidine derivative | 诺华股份有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-104968345-B | 1, 5-naphthyridine derivatives and ME L K inhibitors containing 1, 5-naphthyridine derivatives | 肿瘤疗法科学股份有限公司 | 2018-05-08 | — | — | CN | disclosed |
| CN-106170489-A | New Pyrazolopyrimidine derivative and the purposes as MALT1 inhibitor thereof | 诺华股份有限公司 | 2016-11-30 | — | — | CN | disclosed |
| CN-104968345-A | 1, 5-naphthyridine derivatives and MELK inhibitors containing 1, 5-naphthyridine derivatives | ONCOTHERAPY SCIENCE INC | 2015-10-07 | — | — | CN | disclosed |
| US-4104049-A | Chlorine-substituted vinylaminobenzoic acid compounds and plant growth regulant compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |