Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTGFR | P43088 | 6/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661872 | 0.92 | PTGFR (0.41) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11660406 | 0.90 | PTGFR (0.52) | KDM4EPTGFRTBXA2RPTGER1PTGER3 | |
| SCHEMBL11663400 | 0.90 | PTGFR (0.41) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11654984 | 0.90 | PTGFR (0.42) | KDM4EPTGFRTBXA2RPTGER1PTGER3 | |
| SCHEMBL11660315 | 0.90 | PTGFR (0.41) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11659001 | 0.90 | PTGFR (0.41) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11657736 | 0.89 | PTGIR (0.44) | TSHRMAPK1PTGFRTBXA2RPTGER1 | |
| SCHEMBL11660564 | 0.88 | PTGFR (0.41) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11656835 | 0.87 | PTGFR (0.52) | TSHRKDM4EPTGFRTBXA2RPTGER1 | |
| SCHEMBL11657992 | 0.87 | PTGFR (0.41) | PTGFRTBXA2RPTGER1PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |