Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 9/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11663400 | 0.90 | PTGFR (0.41) | PTGFRPTGER3TBXA2RPTGER1PTGER2 | |
| SCHEMBL11661872 | 0.90 | PTGFR (0.41) | PTGFRPTGER3TBXA2RPTGER1PTGER2 | |
| SCHEMBL11655953 | 0.90 | TSHR (0.45) | PTGFRPTGER3TBXA2RPTGER1PTGER2 | |
| SCHEMBL11654984 | 0.90 | PTGFR (0.42) | PTGFRPTGER3TBXA2RPTGER1PTGER2 | |
| SCHEMBL11659001 | 0.90 | PTGFR (0.41) | PTGFRPTGER3TBXA2RPTGER1PTGER2 | |
| SCHEMBL11660315 | 0.90 | PTGFR (0.41) | PTGFRPTGER3TBXA2RPTGER1PTGER2 | |
| SCHEMBL11657736 | 0.89 | PTGIR (0.44) | PTGFRPTGER3TBXA2RPTGER1PTGER2 | |
| SCHEMBL11660564 | 0.88 | PTGFR (0.41) | PTGFRPTGER3TBXA2RPTGER1PTGER2 | |
| SCHEMBL11662205 | 0.88 | PTGFR (0.51) | PTGFRPTGER3TBXA2RPTGER1PTGER2 | |
| SCHEMBL11657992 | 0.87 | PTGFR (0.41) | PTGFRPTGER3TBXA2RPTGER1PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |