SCHEMBL1165653

SCHEMBL1165653

O=C(O)c1ccc2cc(O)c(C(=O)O)cc2c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.53
PTPN11 Q06124 1/20 0.53
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 3/20 0.50
KDM4E B2RXH2 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
PTGS2 P35354 2/20 0.50
POLB P06746 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
GRIN2D O15399 1/20 0.49
GRIN2A Q12879 1/20 0.49
GRIN2B Q13224 1/20 0.49
GRIN2C Q14957 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30570062 1.00 LCK (0.53) LCKPTPN11CA12CA1CA2
SCHEMBL29812614 1.00 LCK (0.53) LCKPTPN11CA12CA1CA2
SCHEMBL5541003 1.00 LCK (0.53) LCKPTPN11CA12CA1CA2
Hydrochloric Acid SCHEMBL3924510 0.98 LCK (0.52) LCKPTPN11CA12CA1CA2
Potassium SCHEMBL7182313 0.98 LCK (0.52) LCKPTPN11CA12CA1CA2
SCHEMBL7182303 0.98 LCK (0.52) LCKPTPN11CA12CA1CA2
SCHEMBL3391297 0.88 LCK (0.67) LCKPTPN11CA12CA1CA2
SCHEMBL464946 0.88 KDM4E (0.57) LCKPTPN11CA12CA1CA2
SCHEMBL29729046 0.88 KDM4E (0.57) LCKPTPN11CA12CA1CA2
SCHEMBL29779941 0.88 LCK (0.67) LCKPTPN11CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1645584-B1 Method for manufacturing wholly aromatic liquid-crystalline polyester resin UENO SEIYAKU OYO KENKYUJO KK (JP) 2008-06-18 EP claimed
US-7335318-B2 Method for manufacturing wholly aromatic liquid-crystalline polyester resin KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2008-02-26 US claimed
EP-1123914-B1 COLUMNAR CRYSTALS OF 6-HYDROXY-2-NAPHTHOIC ACID AND PROCESS FOR THE PRODUCTION THEREOF UENO FINE CHEMICAL IND (JP) 2007-03-21 EP claimed
US-7179401-B2 Thermotropic liquid-crystalline polymer KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2007-02-20 US claimed
EP-1462468-B1 LIQUID-CRYSTAL POLYESTER RESIN UENO SEIYAKU OYO KENKYUJO KK (JP) 2006-08-02 EP claimed
EP-1422256-B1 THERMOTROPIC LIQUID-CRYSTAL POLYMER UENO SEIYAKU OYO KENKYUJO KK (JP) 2006-08-02 EP claimed
US-20060084747-A1 Method for manufacturing wholly aromatic liquid-crystalline polyester resin KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO 2006-04-20 US claimed
EP-1645584-A1 Method for manufacturing wholly aromatic liquid-crystalline polyester resin KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2006-04-12 EP claimed
US-6984712-B2 Liquid-crystal polyester resin KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2006-01-10 US claimed
US-20050054811-A1 Liquid-crystal polyester resin UENO FINE CHEMICALS INDUSTRY, LTD. (JP) 2005-03-10 US claimed
EP-1422256-A1 THERMOTROPIC LIQUID-CRYSTAL POLYMER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 2004-05-26 EP claimed
EP-0889022-B1 PROCESS FOR PRODUCING 2-HYDROXYNAPHTHALENE-3,6-DICARBOXYLIC ACID UENO SEIYAKU OYO KENKYUJO KK (JP) 2003-04-02 EP claimed
EP-0803492-B1 METHOD FOR SEPARATING AND PURIFYING HYDROXYNAPHTHALENECARBOXYLIC ACIDS UENO SEIYAKU OYO KENKYUJO KK (JP) 2002-02-06 EP claimed
US-6133475-A Process for producing 2-hydroxynaphthalene-3,6-dicarboxylic acid KABUSHIKI KAISHA UENO SEIYAKU OYO KENKUJO (JP) 2000-10-17 US claimed
EP-0889022-A1 PROCESS FOR PRODUCING 2-HYDROXYNAPHTHALENE-3,6-DICARBOXYLIC ACID KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1999-01-07 EP claimed
US-5808142-A Process for the preparation of 2-hydroxynaphthalene-6-carboxylic acid HOECHST AKTIENGESELLSCHAFT (DE) 1998-09-15 US claimed
EP-0625499-B1 Process for the preparation of 2-hydroxynaphthalene-6-carboxylic acid HOECHST AG (DE) 1998-08-26 EP claimed
US-5770766-A NONIONIC POROUS SYNTHETIC ADSORBENT KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-06-23 US claimed
EP-0803492-A1 METHOD FOR SEPARATING AND PURIFYING HYDROXYNAPHTHALENECARBOXYLIC ACIDS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1997-10-29 EP claimed
EP-0625499-A1 Process for the preparation of 2-hydroxynaphthalene-6-carboxylic acid HOECHST AKTIENGESELLSCHAFT (DE) 1994-11-23 EP claimed