SCHEMBL464946

SCHEMBL464946

O=C(O)c1ccc2cc(C(=O)O)c(C(=O)O)cc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.57
PTPN1 P18031 2/20 0.55
PTPN11 Q06124 1/20 0.50
TSHR P16473 2/20 0.48
TP53 P04637 1/20 0.48
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
ENPP2 Q13822 1/20 0.47
HSD17B10 Q99714 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
PTGS2 P35354 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29729046 1.00 KDM4E (0.57) KDM4EPTPN1PTPN11TSHRTP53
SCHEMBL30151493 1.00 KDM4E (0.57) KDM4EPTPN1PTPN11TSHRTP53
SCHEMBL31444254 0.98 KDM4E (0.55) KDM4EPTPN1PTPN11TSHRTP53
SCHEMBL6864591 0.98 KDM4E (0.55) KDM4EPTPN1PTPN11TSHRTP53
SCHEMBL20489383 0.91 PTPN1 (0.61) KDM4EPTPN1PTPN11TP53ALDH1A1
SCHEMBL2803876 0.89 KDM4E (0.51) KDM4EPTPN1PTPN11ALDH1A1HPGD
SCHEMBL1951984 0.88 KDM4E (0.63) KDM4EPTPN1TSHRTP53ALDH1A1
SCHEMBL1552467 0.88 KDM4E (0.63) KDM4EPTPN1TSHRTP53ALDH1A1
SCHEMBL8736492 0.88 KDM4E (0.63) KDM4EPTPN1TSHRTP53ALDH1A1
SCHEMBL1551731 0.88 KDM4E (0.63) KDM4EPTPN1TSHRTP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3143067-B1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2023-09-13 EP claimed
EP-3143067-A1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS Huntsman Advanced Materials Americas LLC (US) 2017-03-22 EP claimed
US-20170051100-A1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2017-02-23 US claimed
CN-106414543-A Multifunctional polyamides for protective coatings 亨斯迈先进材料美国有限责任公司 2017-02-15 CN claimed
WO-2015175583-A1 MULTIFUNCTIONAL POLYAMIDES FOR PROTECTIVE COATINGS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-11-19 WO claimed
US-8859806-B2 Process for purification of aryl carboxylic acids UNIVERSITY OF ALABAMA (US) 2014-10-14 US claimed
US-20130068996-A1 PROCESS FOR PURIFICATION OF ARYL CARBOXYLIC ACIDS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2013-03-21 US claimed
US-20100174111-A1 PROCESS FOR PURIFICATION OF ARYL CARBOXYLIC ACIDS UNIVERSITY OF ALABAMA 2010-07-08 US claimed
WO-2008104999-A2 NOVEL ADDUCTS AS BRANCHING AGENTS FOR CONDENSATION POLYMER AND METHOD FOR PRODUCING THE SAME RELIANCE INDUSTRIES LIMITED (IN) 2008-09-04 WO claimed
US-20080051307-A1 Lubricating Compositions Containing An Ester Of A Polycarboxylic Acylating Agent THE LUBRIZOL CORPORATION (US) 2008-02-28 US claimed
WO-1998012157-A2 PROCESS FOR PURIFICATION OF AROMATIC POLYCARBOXYLIC ACIDS LIN, TSONG-DAR, VINCENT 1998-03-26 WO claimed
US-5395870-A Styrene or acrylic polymer, polyamideimide elastomer, permanent antistatic property, molding materials ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1995-03-07 US claimed
EP-0409995-B1 VINYLIC RESIN COMPOSITION ASAHI CHEMICAL IND (JP) 1994-12-14 EP claimed
EP-0336856-B1 WITH MALEIMIDE GROUPS FUNCTIONALIZED AROMATIC POLYAMIDEIMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR PREPARING CROSS-LINKED POLYMERS CIBA-GEIGY AG (CH) 1993-03-03 EP claimed
EP-0360709-B1 PROCESS FOR THE PREPARATION OF THERMALLY STABLE COPOLYIMIDE AMIDES CONTAINING DIORGANOPOLYSILOXANE GROUPS CIBA-GEIGY AG (CH) 1992-12-16 EP claimed
EP-0334778-B1 AROMATIC POLYAMIDE-IMIDES FUNCTIONALISED WITH ALKENYLOXY GROUPS, A METHOD FOR THEIR PREPARATION AND THEIR USE TO PREPARE CROSSLINKED POLYMERS CIBA-GEIGY AG (CH) 1992-04-15 EP claimed
US-4985527-A Preparation of thermally stable copolyimidoamides containing diorganopolysiloxane recurring units RHONE-POULENC CHIMIE (FR) 1991-01-15 US claimed
US-4927899-A Alkenyloxylated aromatic polyamidoimides RHONE-POULENC CHIMIE (FR) 1990-05-22 US claimed
US-4927900-A Aromatic polyamidoimides having maleimido end groups RHONE-POULENC CHIMIE (FR) 1990-05-22 US claimed
US-4395531-A Process for the preparation of polyamide compounds by the reaction of polycarboxylic acids with diisocyanates in the presence of at least one mono-alkali metal salt of dicarboxylic acid MITSUI TOATSU CHEMICAL INCORPORATED (JP) 1983-07-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100174111-A1 PROCESS FOR PURIFICATION OF ARYL CARBOXYLIC ACIDS DDC, AHR, PAH KDM4E 2780/4885PTPN1 413/4885PTPN11 314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.