SCHEMBL11656646

SCHEMBL11656646

CCCCCCCCCCCCCCCCCCNC(=O)c1cc(NC(=O)C(Cl)(Cl)Cl)c2ccccc2c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.51
PDK1 Q15118 2/20 0.48
PDK2 Q15119 2/20 0.48
PDK3 Q15120 2/20 0.48
PDK4 Q16654 2/20 0.48
USP2 O75604 1/20 0.45
HTT P42858 2/20 0.45
TSHR P16473 1/20 0.45
HPGD P15428 3/20 0.44
ALOX15 P16050 2/20 0.43
BCL2 P10415 1/20 0.43
MCL1 Q07820 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GLA P06280 1/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
APOBEC3A P31941 1/20 0.42
ESR2 Q92731 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11295455 0.84 NAAA (0.58) NAAAUSP2HTTTSHRHPGD
SCHEMBL11598238 0.80 NAAA (0.59) NAAAUSP2HTTTSHRHPGD
SCHEMBL11316839 0.80 NAAA (0.59) NAAAUSP2HTTTSHRHPGD
SCHEMBL9717665 0.80 NAAA (0.66) NAAAUSP2HTTTSHRHPGD
SCHEMBL10707755 0.80 NAAA (0.66) NAAAUSP2HTTTSHRHPGD
SCHEMBL11431283 0.78 NAAA (0.56) NAAAUSP2HTTTSHRHPGD
SCHEMBL11674602 0.78 NAAA (0.56) NAAAUSP2HTTTSHRHPGD
SCHEMBL10934569 0.78 NAAA (0.59) NAAAUSP2HTTTSHRHPGD
SCHEMBL6762498 0.78 NAAA (0.59) NAAAUSP2HTTTSHRHPGD
SCHEMBL10935903 0.78 NAAA (0.59) NAAAUSP2HTTTSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4083721-A AROMATIC PRIMARY AMINE DEVELOPER FUJI PHOTO FILM CO., LTD. (JA) 1978-04-11 US claimed
US-4083721-A AROMATIC PRIMARY AMINE DEVELOPER FUJI PHOTO FILM CO., LTD. (JA) 1978-04-11 US disclosed