Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23812434 | 0.88 | ALDH1A1 (0.63) | TDP1MAPTCYP3A4SLC6A2SLC6A3 | |
| SCHEMBL4758455 | 0.86 | TDP1 (0.73) | TDP1SLC6A2SLC6A3LMNAALDH1A1 | |
| SCHEMBL15341181 | 0.84 | TDP1 (0.74) | TDP1CYP3A4SLC6A2SLC6A3LMNA | |
| SCHEMBL12369122 | 0.84 | ALDH1A1 (0.54) | TDP1MAPTCYP3A4SLC6A2SLC6A3 | |
| SCHEMBL2146000 | 0.84 | ALDH1A1 (0.54) | TDP1MAPTCYP3A4SLC6A2SLC6A3 | |
| SCHEMBL5063447 | 0.84 | CHRM2 (0.54) | TDP1MAPTCYP3A4SLC6A2SLC6A3 | |
| SCHEMBL20695025 | 0.83 | ALDH1A1 (0.57) | TDP1MAPTCYP3A4SLC6A2SLC6A3 | |
| SCHEMBL27968276 | 0.83 | CYP3A4 (0.56) | TDP1MAPTCYP3A4SLC6A2SLC6A3 | |
| SCHEMBL571739 | 0.82 | HTT (0.57) | TDP1MAPTCYP3A4SLC6A2SLC6A3 | |
| SCHEMBL6833259 | 0.82 | TDP1 (0.67) | TDP1CYP3A4SLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101878027-B | Multi-targeted compounds with activity at PPAR and cannabinoid receptors | GIULIANI INT LTD | 2013-01-16 | — | — | CN | disclosed |
| US-20110039808-A1 | Multitarget Compounds Active at a PPAR and Cannabinoid Receptor | NOGRA PHARMA LIMITED (IE) | 2011-02-17 | — | — | US | disclosed |
| US-20110039808-A1 | Multitarget Compounds Active at a PPAR and Cannabinoid Receptor | NOGRA PHARMA LIMITED (IE) | 2011-02-17 | — | — | US | disclosed |
| US-20110039808-A1 | Multitarget Compounds Active at a PPAR and Cannabinoid Receptor | NOGRA PHARMA LIMITED (IE) | 2011-02-17 | — | — | US | disclosed |
| CN-101878027-A | Multi-targeted compounds with activity at PPAR and cannabinoid receptors | GIULIANI INT LTD | 2010-11-03 | — | — | CN | disclosed |
| EP-2222287-A2 | MULTITARGET COMPOUNDS ACTIVE AT A PPAR AND CANNABINOID RECEPTOR | Giuliani International Limited (IE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009080821-A2 | RECEPTOR TARGETING LIGANDS | GIULIANI INTERNATIONAL LIMITED (IE) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039808-A1 | Multitarget Compounds Active at a PPAR and Cannabinoid Receptor | PPARA, PPARG, PPARD | TDP1 4478/4885MAPT 3469/4885CYP3A4 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.