Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | CBR1 | P16152 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29071642 | 0.85 | APP (0.49) | APPALOX5MAPTHCAR2TTR | |
| SCHEMBL305978 | 0.81 | APP (0.49) | APPALOX5ALDH1A1MAPTHCAR2 | |
| SCHEMBL29071475 | 0.77 | APP (0.42) | APPALOX5ALDH1A1HCAR2TTR | |
| SCHEMBL19377862 | 0.77 | MAPT (0.54) | ALDH1A1MAPTTDP1L3MBTL1HPGD | |
| SCHEMBL11623017 | 0.77 | MAPT (0.54) | ALDH1A1MAPTTDP1L3MBTL1HPGD | |
| SCHEMBL17513205 | 0.77 | MAPT (0.54) | ALDH1A1MAPTTDP1L3MBTL1HPGD | |
| SCHEMBL28507077 | 0.74 | MAPT (0.45) | ALDH1A1MAPTL3MBTL1HPGDTTR | |
| SCHEMBL28439526 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1HPGDTTR | |
| Methacrylic Acid SCHEMBL28158788 | 0.73 | APP (0.42) | APPALOX5ALDH1A1HCAR2HPGD | |
| SCHEMBL28478347 | 0.73 | APP (0.38) | APPALOX5ALDH1A1TDP1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4120721-A | ACRYLIC OR METHACRYLIC TERMINATED, URETHANE CONTAINING POLYENE; WATER INSOLUBLE VINYL MONOMER DILUENT; POLYTHIOL; PHOTOINITIATOR | W. R. GRACE & CO. (US) | 1978-10-17 | — | — | US | disclosed |