Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11650221 | 0.91 | PLK1 (0.41) | PLK1ALDH1A1HAO1L3MBTL1PDE4B | |
| Ethylene SCHEMBL11651022 | 0.89 | HAO1 (0.40) | PLK1ALDH1A1HAO1L3MBTL1PDE4B | |
| SCHEMBL7196791 | 0.86 | L3MBTL1 (0.55) | PLK1HAO1L3MBTL1HSD17B3MMP2 | |
| SCHEMBL457406 | 0.83 | PLK1 (0.45) | PLK1ALDH1A1HAO1L3MBTL1MMP2 | |
| Ethylene SCHEMBL11649493 | 0.82 | NPC1 (0.45) | HAO1L3MBTL1HSD17B3MMP2MMP9 | |
| SCHEMBL17831000 | 0.81 | KMT2A (0.55) | ALDH1A1L3MBTL1PDE4BHSD17B3HDAC8 | |
| SCHEMBL20243167 | 0.81 | L3MBTL1 (0.55) | ALDH1A1L3MBTL1PDE4BHSD17B3HDAC8 | |
| SCHEMBL6138941 | 0.80 | HAO1 (0.44) | PLK1ALDH1A1HAO1L3MBTL1PDE4B | |
| SCHEMBL6138736 | 0.80 | HAO1 (0.56) | PLK1HAO1L3MBTL1PDE4BHSD17B3 | |
| SCHEMBL11656990 | 0.80 | HAO1 (0.47) | PLK1HAO1L3MBTL1HSD17B3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4081551-A | OXIME ETHERS HAVING ANTI-DEPRESSIVE ACTIVITY | U.S. PHILIPS CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |