Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.55 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662319 | 0.95 | FFAR4 (0.54) | FFAR4FFAR1PLA2G2CCYP1A2CYP3A4 | |
| SCHEMBL11657156 | 0.88 | FFAR4 (0.51) | FFAR4FFAR1ALDH1A1TBXAS1GPR84 | |
| SCHEMBL9629085 | 0.86 | FFAR4 (0.70) | FFAR4FFAR1PLA2G2CCYP1A2CYP3A4 | |
| SCHEMBL28747247 | 0.84 | FFAR4 (0.67) | FFAR4FFAR1PLA2G2CCYP1A2CYP3A4 | |
| SCHEMBL9630851 | 0.84 | FFAR4 (0.67) | FFAR4FFAR1PLA2G2CCYP1A2CYP3A4 | |
| SCHEMBL9628887 | 0.84 | FFAR4 (0.67) | FFAR4FFAR1PLA2G2CCYP1A2CYP3A4 | |
| SCHEMBL11615905 | 0.84 | FFAR4 (0.77) | FFAR4FFAR1ALDH1A1ALOX15GPR84 | |
| SCHEMBL11618654 | 0.84 | FFAR4 (0.77) | FFAR4FFAR1ALDH1A1ALOX15GPR84 | |
| SCHEMBL7550732 | 0.84 | FFAR4 (0.77) | FFAR4FFAR1ALDH1A1ALOX15GPR84 | |
| SCHEMBL11615881 | 0.84 | FFAR4 (0.77) | FFAR4FFAR1ALDH1A1ALOX15GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4020177-A | CONTRACEPTIVES | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |