Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662319 | 0.90 | FFAR4 (0.54) | FFAR4FFAR1TBXAS1ALDH1A1GPR84 | |
| SCHEMBL11657073 | 0.88 | FFAR4 (0.55) | FFAR4FFAR1TBXAS1ALDH1A1GPR84 | |
| SCHEMBL11659103 | 0.87 | FFAR4 (0.46) | FFAR4FFAR1TBXAS1ALDH1A1 | |
| SCHEMBL11615905 | 0.82 | FFAR4 (0.77) | FFAR4FFAR1ALDH1A1GPR84FAAH | |
| SCHEMBL11615881 | 0.82 | FFAR4 (0.77) | FFAR4FFAR1ALDH1A1GPR84FAAH | |
| SCHEMBL7550732 | 0.82 | FFAR4 (0.77) | FFAR4FFAR1ALDH1A1GPR84FAAH | |
| SCHEMBL11618654 | 0.82 | FFAR4 (0.77) | FFAR4FFAR1ALDH1A1GPR84FAAH | |
| SCHEMBL11656722 | 0.82 | FFAR4 (0.41) | FFAR4FFAR1TBXAS1ALDH1A1TBXA2R | |
| SCHEMBL11657458 | 0.81 | CA1 (0.45) | FFAR4FFAR1TBXAS1 | |
| SCHEMBL11613594 | 0.80 | FFAR4 (0.69) | FFAR4FFAR1ALDH1A1GPR84TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4020177-A | CONTRACEPTIVES | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |