Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PTGFR | P43088 | 3/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657383 | 0.89 | TBXA2R (0.47) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11661911 | 0.89 | PTGFR (0.46) | PTGFRTBXA2RPTGER1PTGER3LMNA | |
| SCHEMBL11658378 | 0.89 | TBXA2R (0.56) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11661817 | 0.88 | PTGER1 (0.46) | TSHRMAPK1PTGFRTBXA2RPTGER1 | |
| SCHEMBL11662117 | 0.88 | ABCB1 (0.49) | TSHRKDM4EPTGFRTBXA2RPTGER1 | |
| SCHEMBL11654409 | 0.88 | PTGER1 (0.46) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11655915 | 0.88 | PTGFR (0.61) | KDM4EPTGFRTBXA2RPTGER1PTGER3 | |
| SCHEMBL11654416 | 0.88 | PTGFR (0.48) | KDM4EPTGFRTBXA2RPTGER1PTGER3 | |
| SCHEMBL11656559 | 0.88 | TSHR (0.48) | TSHRMAPK1KDM4EMTNR1AMTNR1B | |
| SCHEMBL11658722 | 0.87 | MAPK1 (0.46) | TSHRMAPK1KDM4EPTGFRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4020177-A | CONTRACEPTIVES | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |