Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.46 |
| ▸ | PTGFR | P43088 | 3/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FOS | P01100 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662117 | 0.89 | ABCB1 (0.49) | PTGER1PTGER3PTGFRTBXA2RPTGER2 | |
| SCHEMBL11657093 | 0.88 | TSHR (0.50) | PTGER1PTGER3PTGFRTBXA2RPTGER2 | |
| SCHEMBL11657383 | 0.88 | TBXA2R (0.47) | PTGER1PTGER3PTGFRTBXA2RPTGER2 | |
| SCHEMBL11659488 | 0.88 | HPGD (0.37) | PTGER1PTGER3PTGFRTBXA2RPTGER2 | |
| SCHEMBL11658378 | 0.88 | TBXA2R (0.56) | PTGER1PTGER3PTGFRTBXA2RPTGER2 | |
| SCHEMBL11655915 | 0.87 | PTGFR (0.61) | PTGER1PTGER3PTGFRTBXA2RPTGER2 | |
| SCHEMBL11654409 | 0.87 | PTGER1 (0.46) | PTGER1PTGER3PTGFRTBXA2RPTGER2 | |
| SCHEMBL11654416 | 0.87 | PTGFR (0.48) | PTGER1PTGER3PTGFRTBXA2RPTGER2 | |
| SCHEMBL11658722 | 0.86 | MAPK1 (0.46) | PTGER1PTGER3PTGFRTBXA2RPTGER2 | |
| SCHEMBL11659001 | 0.86 | PTGFR (0.41) | PTGER1PTGER3PTGFRTBXA2RPTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4020177-A | CONTRACEPTIVES | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |