Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11650422 | 1.00 | GAA (0.45) | GAATHRBTSHRKMT2AHTT | |
| SCHEMBL10548922 | 0.89 | GAA (0.50) | GAATHRBTSHRKMT2AHTT | |
| SCHEMBL11646076 | 0.86 | THRB (0.45) | GAATHRBTSHRKMT2AHTT | |
| SCHEMBL11667997 | 0.86 | THRB (0.45) | GAATHRBTSHRKMT2AHTT | |
| SCHEMBL18124228 | 0.86 | GAA (0.48) | GAATHRBTSHRKMT2AHTT | |
| SCHEMBL11650842 | 0.85 | GAA (0.48) | GAATSHRKMT2AHTTTDP1 | |
| SCHEMBL11298132 | 0.85 | THRB (0.46) | GAATHRBTSHRKMT2AHTT | |
| SCHEMBL11668133 | 0.81 | GAA (0.55) | GAATHRBTSHRKMT2AHTT | |
| SCHEMBL17548966 | 0.81 | GAA (0.50) | GAATHRBTSHRKMT2AHTT | |
| SCHEMBL11654877 | 0.81 | THRB (0.45) | GAATHRBTSHRKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117240-A | CONTAINING ANTIOXIDANT PHENOLIC DERIVATIVES OF ACRYLIC ESTERS AS MONOMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-3962187-A | STABILIZED POLYMERS OF DITERTIARY ALKYL-4-HYDROXYBENZYLOXY ALKYL ACRYLATES AND DIENES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-06-08 | — | — | US | disclosed |