Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | SCN4A | P35499 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080744 | 0.78 | TAAR1 (0.38) | TAAR1HTR2AIDO1SCN4A | |
| SCHEMBL11658702 | 0.76 | SCN4A (0.42) | TAAR1HTR2ASCN4A | |
| SCHEMBL7151065 | 0.74 | TAAR1 (0.40) | TAAR1IDO1 | |
| SCHEMBL8518741 | 0.74 | TAAR1 (0.40) | TAAR1HTR2AIDO1 | |
| SCHEMBL11661173 | 0.71 | HTR2C (0.38) | TAAR1HTR2A | |
| SCHEMBL11658725 | 0.71 | TAAR1 (0.37) | TAAR1HTR2AIDO1 | |
| SCHEMBL11364826 | 0.71 | TAAR1 (0.43) | TAAR1IDO1 | |
| Hydrochloric Acid SCHEMBL28805848 | 0.70 | TAAR1 (0.35) | TAAR1HTR2AIDO1 | |
| SCHEMBL5167903 | 0.68 | GABRA1 (0.43) | TAAR1SCN4A | |
| SCHEMBL1815884 | 0.68 | GABRA1 (0.43) | TAAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129661-A | 4,5-Dihydro-2-lower alkoxycarbonylamino-4-phenylimidazoles and substituted phenyl derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1978-12-12 | — | — | US | disclosed |