Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14349951 | 0.90 | RAB9A (0.58) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL8868795 | 0.89 | RAB9A (0.54) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL6404645 | 0.89 | NPC1 (0.54) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL6405063 | 0.88 | CYP4F2 (0.53) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2088667 | 0.87 | POLB (0.64) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL1903659 | 0.85 | CYP4F2 (0.58) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL8867661 | 0.85 | RAB9A (0.56) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL2019464 | 0.84 | POLB (0.70) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL7565510 | 0.84 | RAB9A (0.71) | HPGDALDH1A1POLBNPC1RAB9A | |
| SCHEMBL2088666 | 0.84 | POLB (0.60) | HPGDALDH1A1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069240-A | GROUP 8 METAL CATALYST | UNIROYAL, INC. (US) | 1978-01-17 | — | — | US | disclosed |