Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659055 | 0.86 | ABCB11 (0.43) | MAPTKMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL11661721 | 0.80 | SMN1; SMN2 (0.38) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL708213 | 0.77 | MAPT (0.59) | MAPTKMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL1832142 | 0.71 | MAPT (0.44) | MAPTKMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL1832145 | 0.71 | MAPT (0.44) | MAPTKMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL6977075 | 0.68 | CHRM2 (0.48) | MAPTKMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL1626657 | 0.68 | CNR2 (0.48) | MAPTKMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL22164189 | 0.68 | MAPT (0.46) | MAPTKMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL31294663 | 0.68 | KMT2A (0.46) | MAPTKMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL19183403 | 0.67 | MAPT (0.49) | MAPTKMT2AMEN1NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073936-A | Hypolipidemic allene carboxylic esters | SANDOZ, INC. (US) | 1978-02-14 | — | — | US | claimed |
| US-4073936-A | Hypolipidemic allene carboxylic esters | SANDOZ, INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4011339-A | ANTIINFLAMMATORY AGENTS | SANDOZ, INC. (US) | 1977-03-08 | — | — | US | disclosed |