Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.66 |
| ▸ | RAB9A | P51151 | 12/20 | 0.66 |
| ▸ | POLB | P06746 | 4/20 | 0.66 |
| ▸ | CASP3 | P42574 | 2/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
| ▸ | RELA | Q04206 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783463 | 0.84 | NPC1 (0.60) | NPC1RAB9APOLBCASP3SENP7 | |
| SCHEMBL1673429 | 0.82 | BAZ2B (0.69) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL987970 | 0.81 | ATM (0.68) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL31169451 | 0.81 | NPC1 (0.57) | NPC1RAB9APOLBCASP3SENP7 | |
| SCHEMBL11657866 | 0.81 | RAB9A (0.63) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL11896022 | 0.80 | NPC1 (0.70) | NPC1RAB9APOLBCASP3SENP7 | |
| SCHEMBL29791442 | 0.80 | NPC1 (0.64) | NPC1RAB9APOLBCASP3SENP7 | |
| SCHEMBL3003689 | 0.80 | F2 (0.54) | MEN1KMT2A | |
| SCHEMBL15890231 | 0.80 | NPC1 (0.64) | NPC1RAB9APOLBCASP3SENP7 | |
| SCHEMBL4106288 | 0.80 | NPC1 (1.00) | NPC1RAB9APOLBCASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069240-A | GROUP 8 METAL CATALYST | UNIROYAL, INC. (US) | 1978-01-17 | — | — | US | disclosed |