Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK2 | Q13002 | 2/20 | 0.67 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.67 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11688432 | 0.88 | GRIK1 (0.52) | GRIK2GRIK1NLRP3L3MBTL1ADORA1 | |
| SCHEMBL18470545 | 0.84 | GRIK1 (0.49) | GRIK2GRIK1NLRP3ACLYKMT2A | |
| SCHEMBL18470542 | 0.84 | GRIK1 (0.49) | GRIK2GRIK1NLRP3L3MBTL1ACLY | |
| SCHEMBL18470548 | 0.84 | GRIK1 (0.49) | GRIK2GRIK1NLRP3L3MBTL1ACLY | |
| SCHEMBL31413549 | 0.83 | GRIK1 (0.65) | GRIK2GRIK1NLRP3L3MBTL1ADORA1 | |
| SCHEMBL1171837 | 0.83 | GRIK1 (0.65) | GRIK2GRIK1NLRP3L3MBTL1ADORA1 | |
| SCHEMBL16760311 | 0.83 | CYP11B1 (0.49) | GRIK2GRIK1NLRP3ALDH1A1KDM4E | |
| SCHEMBL2421447 | 0.83 | GRIK1 (0.65) | GRIK2GRIK1NLRP3L3MBTL1ADORA1 | |
| SCHEMBL8648612 | 0.83 | GRIK1 (0.65) | GRIK2GRIK1NLRP3L3MBTL1ACLY | |
| SCHEMBL11660487 | 0.82 | GRIK1 (0.52) | GRIK2GRIK1NLRP3L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104268-A | POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |