Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31413549 | 0.88 | GRIK1 (0.65) | GRIK1GRIK2L3MBTL1ALDH1A1MTNR1A | |
| SCHEMBL1171837 | 0.88 | GRIK1 (0.65) | GRIK1GRIK2L3MBTL1ALDH1A1MTNR1A | |
| SCHEMBL11659573 | 0.87 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1MTNR1AMTNR1BKMT2A | |
| SCHEMBL18806865 | 0.86 | GRIK1 (0.54) | GRIK1GRIK2L3MBTL1ALDH1A1MTNR1A | |
| SCHEMBL11312995 | 0.85 | L3MBTL1 (0.53) | GRIK1GRIK2L3MBTL1ALDH1A1MTNR1A | |
| SCHEMBL5661209 | 0.85 | PTGS2 (0.61) | GRIK1GRIK2L3MBTL1ALDH1A1MTNR1A | |
| SCHEMBL11659560 | 0.84 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1MTNR1AMTNR1BKMT2A | |
| SCHEMBL11664568 | 0.84 | GRIK1 (0.50) | GRIK1GRIK2L3MBTL1ALDH1A1MTNR1A | |
| SCHEMBL1171750 | 0.83 | GRIK1 (0.60) | GRIK1GRIK2L3MBTL1ALDH1A1MTNR1A | |
| SCHEMBL5700736 | 0.83 | GRIK1 (0.60) | GRIK1GRIK2L3MBTL1ALDH1A1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104268-A | POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-3993645-A | Stilbene optical brighteners and compositions brightened therewith | STERLING DRUG INC. (US) | 1976-11-23 | — | — | US | disclosed |
| US-3932301-A | NYLON, POLYESTERS | STERLING DRUG INC. (US) | 1976-01-13 | — | — | US | disclosed |