Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657980 | 0.91 | HTR2A (0.50) | HTR2ATLR8HTR1AHTR1DHTR1B | |
| SCHEMBL9249543 | 0.87 | HTR2A (0.49) | HTR2ATLR8HTR1AHTR1DHTR1B | |
| SCHEMBL21954855 | 0.83 | SKP2 (0.44) | HTR2ATLR8HTR1AHTR1DHTR1B | |
| SCHEMBL11626934 | 0.81 | HTR2A (0.44) | HTR2ATLR8HTR1AHTR1DHTR1B | |
| SCHEMBL31003469 | 0.77 | HTR2A (0.56) | HTR2ATLR8HTR1AHTR1DHTR1B | |
| SCHEMBL12502918 | 0.77 | HTR2A (0.66) | HTR2AS1PR1S1PR4S1PR5ESR1 | |
| SCHEMBL11664454 | 0.77 | HTR2A (0.66) | HTR2AS1PR1S1PR4S1PR5ESR1 | |
| SCHEMBL9862310 | 0.76 | PTGS2 (0.53) | HTR2ATLR8GPR3ESR1ADRA2A | |
| SCHEMBL9862240 | 0.76 | PTGS2 (0.53) | HTR2ATLR8GPR3ESR1ADRA2A | |
| Hydrochloric Acid SCHEMBL27921087 | 0.76 | HTR2A (0.64) | HTR2AS1PR1S1PR4S1PR5ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129661-A | 4,5-Dihydro-2-lower alkoxycarbonylamino-4-phenylimidazoles and substituted phenyl derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1978-12-12 | — | — | US | disclosed |