Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.79 |
| ▸ | MAPT | P10636 | 4/20 | 0.79 |
| ▸ | MEN1 | O00255 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | HPGD | P15428 | 3/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.79 |
| ▸ | USP2 | O75604 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.79 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ITK | Q08881 | 4/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478915 | 0.89 | KDM4E (1.00) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL10937804 | 0.85 | MAPT (0.67) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL11653092 | 0.83 | KDM4E (0.59) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| 2-(2'-Hydroxyphenyl)-1H-Indole SCHEMBL30486077 | 0.82 | KDM4E (0.68) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| 2-(2'-Hydroxyphenyl)-1H-Indole SCHEMBL6742396 | 0.82 | KDM4E (0.68) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL11498132 | 0.82 | KDM4E (0.72) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL9512915 | 0.82 | KDM4E (0.68) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL8965861 | 0.81 | KDM4E (0.62) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL10215069 | 0.80 | MEN1 (0.52) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL11652930 | 0.80 | KDM4E (0.72) | KDM4EMAPTMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096112-A | POLYVINYL CHLORIDE | LABAZ (FR) | 1978-06-20 | — | — | US | disclosed |
| US-4024155-A | 2-(3'-Methoxy-4'-hydroxy-phenol)-indole | LABAZ (FR) | 1977-05-17 | — | — | US | disclosed |