Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | F2 | P00734 | 1/20 | 0.60 |
| ▸ | F10 | P00742 | 1/20 | 0.60 |
| ▸ | PLG | P00747 | 1/20 | 0.60 |
| ▸ | PLAU | P00749 | 1/20 | 0.60 |
| ▸ | PLAT | P00750 | 1/20 | 0.60 |
| ▸ | HPN | P05981 | 1/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-(2'-Hydroxyphenyl)-1H-Indole SCHEMBL30486077 | 1.00 | KDM4E (0.68) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| 2-(2'-Hydroxyphenyl)-1H-Indole SCHEMBL22418991 | 0.92 | KDM4E (0.59) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL11498132 | 0.88 | KDM4E (0.72) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL9293419 | 0.86 | KDM4E (0.56) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL5051826 | 0.86 | KDR (0.68) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL11653092 | 0.85 | KDM4E (0.59) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL8965861 | 0.84 | KDM4E (0.62) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL30579770 | 0.84 | KDM4E (0.71) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL11792887 | 0.84 | KDM4E (0.71) | KDM4EMAPTMEN1ALDH1A1HPGD | |
| Methane SCHEMBL28704887 | 0.84 | KDR (0.66) | KDM4EMAPTMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105541826-A | Zinc ion fluorescence probe compound, preparation method and application | INST OF AGRO-FOOD SCIENCE AND TECH CHINESE ACAD OF AGRICULTURAL SCIENCES | 2016-05-04 | — | — | CN | claimed |
| US-20150272928-A1 | INDOLE DERIVATIVES | UNIVERSITY OF CENTRAL LANCASHIRE (GB) | 2015-10-01 | — | — | US | claimed |
| EP-2900235-A1 | INDOLE DERIVATIVES | University of Central Lancashire (GB) | 2015-08-05 | — | — | EP | claimed |
| US-4132714-A | Production of chromenoindole compounds | CIBA-GEIGY CORPORATION (US) | 1979-01-02 | — | — | US | claimed |
| US-3931228-A | Process for preparing phthalide and naphthalide indicator dyes | POLAROID CORPORATION (US) | 1976-01-06 | — | — | US | claimed |
| CN-116396302-B | Indole compound and preparation method thereof | 南京工业大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-116396302-B | Indole compound and preparation method thereof | 南京工业大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-116916912-A | Protein toxicity of sulfated C19 steroid hormone for treatment and/or prevention of protein aggregation disease | 帕布罗·德奥拉韦德大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-116801877-A | Epididymal sulfate and/or steroid sulfatase inhibitors for treating or improving age-related cognitive impairment | 帕布罗·德奥拉韦德大学 | 2023-09-22 | — | — | CN | disclosed |
| EP-3621957-B1 | FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES | AMBIENT PHOTONICS INC (US) | 2023-08-23 | — | — | EP | disclosed |
| CN-116396302-A | Indole compound and preparation method thereof | 南京工业大学 | 2023-07-07 | — | — | CN | disclosed |
| CN-116396302-A | Indole compound and preparation method thereof | 南京工业大学 | 2023-07-07 | — | — | CN | disclosed |
| US-4001277-A | INDICATOR DYES, OPTICAL FILTERS, PHOTOGRAPHY | POLAROID CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-4001278-A | INDOLE PHTHALIDES AND NAPHTHALIDES | POLAROID CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-3976659-A | INDICATORS | POLAROID CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3976662-A | 1:1 Adducts of 1-naphthol and (Na)phthalaldehydic acid | POLAROID CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3954799-A | Protonated indole phthalides and naphthalides | POLAROID CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
| US-3941807-A | Indole dehydro phthalides and naphthalides | POLAROID CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |
| US-3932455-A | INDICATOR DYES, PHOTOGRAPHIC FILTERS | POLAROID CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
| US-3931228-A | Process for preparing phthalide and naphthalide indicator dyes | POLAROID CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150272928-A1 | INDOLE DERIVATIVES | IDO1, TPH1, IDO2 | KDM4E 572/4885MAPT 3268/4885MEN1 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.