Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566798 | 0.89 | AKR1B1 (0.52) | AKR1B1MAPK14ALDH1A1MAPTLMNA | |
| SCHEMBL11566488 | 0.82 | MEN1 (0.34) | AKR1B1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL11568284 | 0.80 | AKR1B1 (0.38) | AKR1B1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL11564650 | 0.80 | CA12 (0.40) | AKR1B1ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL11564321 | 0.78 | AKR1B1 (0.47) | AKR1B1MAPK14ALDH1A1LMNACTNNB1 | |
| SCHEMBL11567792 | 0.78 | AKR1B1 (0.52) | AKR1B1MAPK14ALDH1A1MAPTCTNNB1 | |
| SCHEMBL11659196 | 0.78 | AKR1B1 (0.53) | AKR1B1MAPK14ALDH1A1MAPTLMNA | |
| SCHEMBL11820581 | 0.77 | AKR1B1 (0.68) | AKR1B1MAPK14ALDH1A1MAPTLMNA | |
| SCHEMBL11566471 | 0.77 | AKR1B1 (0.60) | AKR1B1MAPK14ALDH1A1MAPTTTR | |
| SCHEMBL11567084 | 0.76 | AKR1B1 (0.54) | AKR1B1MAPK14ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130654-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, FRIBRINOLYTIC, MUSCLE RELAXANT | SYNTEX (U.S.A.) INC. (US) | 1978-12-19 | — | — | US | disclosed |