Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564650 | 0.88 | CA12 (0.40) | AKR1B1TP53SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL11566488 | 0.86 | MEN1 (0.34) | AKR1B1TP53SMN1; SMN2GAAKMT2A | |
| SCHEMBL11639600 | 0.85 | LMNA (0.41) | AKR1B1TP53SMN1; SMN2GAAKMT2A | |
| SCHEMBL11565297 | 0.81 | AKR1B1 (0.44) | AKR1B1TP53GAAKMT2ANPC1 | |
| SCHEMBL11659849 | 0.80 | AKR1B1 (0.49) | AKR1B1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL11566798 | 0.78 | AKR1B1 (0.52) | AKR1B1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL11563438 | 0.78 | AKR1B1 (0.47) | AKR1B1TP53GAAKMT2ANPC1 | |
| SCHEMBL11658676 | 0.77 | SRD5A2 (0.55) | AKR1B1TP53SMN1; SMN2GAAKMT2A | |
| SCHEMBL11566981 | 0.77 | AKR1B1 (0.44) | AKR1B1TP53GAAKMT2ANPC1 | |
| SCHEMBL11659100 | 0.76 | AKR1B1 (0.41) | AKR1B1TP53GAAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003422-A1 | Novel 4-(8X-6,11-dihydrodibenzo-(b,e)-thiepin-11-one-3-yl)-4-oxobutyric acids, methods of preparation, compositions and uses thereof | SYNTEX (U.S.A.) INC. (US) | 1979-08-08 | — | — | EP | disclosed |
| US-4130654-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, FRIBRINOLYTIC, MUSCLE RELAXANT | SYNTEX (U.S.A.) INC. (US) | 1978-12-19 | — | — | US | disclosed |