Butadiene

Butadiene

SCHEMBL116599

C=CC=C.N#CC=CC=Cc1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.54
ALDH1A1 P00352 3/20 0.42
LMNA P02545 3/20 0.42
MAPK1 P28482 2/20 0.42
TRPA1 O75762 1/20 0.42
ALOX5 P09917 1/20 0.42
MCL1 Q07820 2/20 0.40
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butadiene SCHEMBL27850381 1.00 MAOB (0.54) MAOBALDH1A1LMNAMAPK1TRPA1
Acrylonitrile SCHEMBL8948878 0.96 MAOB (0.50) MAOBALDH1A1LMNAMAPK1TRPA1
Styrene SCHEMBL461688 0.95 ALDH1A1 (0.48) MAOBALDH1A1LMNAMAPK1TRPA1
Styrene SCHEMBL2880602 0.95 ALDH1A1 (0.48) MAOBALDH1A1LMNAMAPK1TRPA1
SCHEMBL27794334 0.94 MAOB (0.52) MAOBALDH1A1LMNAMAPK1TRPA1
Butadiene SCHEMBL11243540 0.93 MAOB (0.47) MAOBALDH1A1LMNAMAPK1TRPA1
SCHEMBL9817383 0.93 MAOB (0.50) MAOBALDH1A1LMNAMAPK1TRPA1
SCHEMBL7159537 0.93 MAOB (0.50) MAOBALDH1A1LMNAMAPK1TRPA1
SCHEMBL8948870 0.93 MAOB (0.50) MAOBALDH1A1LMNAMAPK1TRPA1
Acrylonitrile SCHEMBL123982 0.92 MAOB (0.54) MAOBALDH1A1LMNAMAPK1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2368 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3733399-B1 BLOCK COPOLYMER COMPOSITION, PREPREGS, AND LAMINATES MADE THEREFROM KRATON POLYMERS RES BV (NL) 2024-04-24 EP claimed
CN-117565354-A Plastic preparation device and method 四川恒领皓睿塑胶科技有限公司 2024-02-20 CN claimed
CN-115873356-B Styrene-based composition with high electroplating performance and preparation method thereof 金发科技股份有限公司 2024-02-06 CN claimed
CN-111875916-B Block copolymer composition, prepreg, and laminate prepared therefrom 克拉通聚合物研究有限公司 2023-12-12 CN claimed
CN-116964133-A Condensation curable composition comprising a siloxane-imide crosslinker 迈图高新材料公司 2023-10-27 CN claimed
CN-116904010-A Spray-free flow mark effect polycarbonate plastic material and preparation method thereof 上海金山锦湖日丽塑料有限公司 2023-10-20 CN claimed
CN-116917382-A Siloxane-imide copolymer and addition-curable composition containing same 迈图高新材料公司 2023-10-20 CN claimed
CN-116897179-A Addition-curable composition comprising siloxane-imide copolymer 迈图高新材料公司 2023-10-17 CN claimed
CN-116888194-A Condensation curable composition comprising a siloxane-imide base polymer 迈图高新材料公司 2023-10-13 CN claimed
CN-112341970-B Epoxy structural adhesive and preparation method thereof 深圳市安伯斯科技有限公司 2023-08-29 CN claimed
US-4527712-A Method and apparatus for dispensing liquid compositions NORDSON CORPORATION (US) 1985-07-09 US claimed
EP-0078593-B1 A SYSTEM OF A SHOWER TRAY, WASTE AND SUPPORT PLASTIC FINISHES LIMITED (GB) 1985-06-19 EP claimed
US-4497924-A POLYMER OF BISPHENOL COMPOUND AND A DIHALOMETHANE UNION CARBIDE CORPORATION (US) 1985-02-05 US claimed
EP-0069793-A1 Polyarylate containing blends AMOCO CORPORATION (US) 1983-01-19 EP claimed
EP-0035661-A2 Continuous process for the removal of monomers from polymeric emulsions Montedison S.p.A. (IT) 1981-09-16 EP claimed
US-4277364-A Encapsulation by entrapment THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1981-07-07 US claimed
US-4252911-A Mass polymerization process for ABS polyblends MONSANTO COMPANY (US) 1981-02-24 US claimed
US-3961987-A ELECTRO-CATALYST AND PROCESS OF MANUFACTURE SIEMENS AKTIENGESELLSCHAFT (DT) 1976-06-08 US claimed
US-3962156-A ALDEHYDE-PHENOL-POLYAMINE REACTION PRODUCT ROHM AND HAAS COMPANY (US) 1976-06-08 US claimed
US-3931356-A POLYMERIZATION MONSANTO COMPANY (US) 1976-01-06 US claimed