Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 6/20 | 0.42 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM4B | O94953 | 1/20 | 0.42 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11621808 | 1.00 | MAPK1 (0.49) | MAPK1TSHRVCAM1L3MBTL1ALDH1A1 | |
| SCHEMBL11741510 | 0.88 | MAPK1 (0.57) | MAPK1TSHRVCAM1L3MBTL1ALDH1A1 | |
| SCHEMBL11741496 | 0.88 | MAPK1 (0.57) | MAPK1TSHRVCAM1L3MBTL1ALDH1A1 | |
| SCHEMBL4658918 | 0.87 | MAPK1 (0.53) | MAPK1TSHRVCAM1L3MBTL1ALDH1A1 | |
| SCHEMBL29708112 | 0.82 | MAPK1 (0.55) | MAPK1TSHRVCAM1L3MBTL1ALDH1A1 | |
| SCHEMBL203086 | 0.82 | MAPK1 (0.55) | MAPK1TSHRVCAM1L3MBTL1ALDH1A1 | |
| SCHEMBL10796835 | 0.81 | VCAM1 (0.51) | MAPK1TSHRVCAM1L3MBTL1ALDH1A1 | |
| SCHEMBL11746111 | 0.80 | MAPT (0.53) | MAPK1TSHRVCAM1L3MBTL1PDE7A | |
| SCHEMBL11746100 | 0.80 | MAPT (0.53) | MAPK1TSHRVCAM1L3MBTL1PDE7A | |
| SCHEMBL11618923 | 0.80 | TSHR (0.55) | MAPK1TSHRALDH1A1SOS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087549-A | Sulphonic acid containing indenyl derivatives | MERCK & CO., INC. (US) | 1978-05-02 | — | — | US | disclosed |