Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CASP7 | P55210 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17045730 | 0.81 | PARP1 (0.53) | PARP1NPSR1GSK3BMEN1KMT2A | |
| SCHEMBL1024613 | 0.80 | GSK3B (0.46) | PARP1NPSR1GSK3BMEN1KMT2A | |
| SCHEMBL6848270 | 0.79 | PARP1 (0.63) | PARP1NPSR1GSK3BMEN1KMT2A | |
| SCHEMBL29089233 | 0.77 | PARP1 (0.66) | PARP1NPSR1GSK3BMEN1KMT2A | |
| SCHEMBL1756367 | 0.76 | PARP1 (0.63) | PARP1NPSR1GSK3BMEN1KMT2A | |
| SCHEMBL21450709 | 0.76 | PARP1 (0.63) | PARP1NPSR1GSK3BMEN1KMT2A | |
| SCHEMBL28935123 | 0.76 | PARP1 (0.63) | PARP1NPSR1GSK3BMEN1KMT2A | |
| SCHEMBL339347 | 0.76 | PARP1 (0.63) | PARP1NPSR1GSK3BMEN1KMT2A | |
| SCHEMBL3852142 | 0.76 | PARP1 (0.63) | PARP1NPSR1GSK3BMEN1KMT2A | |
| SCHEMBL29053384 | 0.76 | PARP1 (0.63) | PARP1NPSR1GSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998841-A | CHLOROTHIO-N-PHTHALIMIDE AND PROCESS THEREFOR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | claimed |
| US-4080399-A | REACTING N-CHLOROTHIOPHTHALIMIDE WITH UNSATURATED COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |
| US-3998841-A | CHLOROTHIO-N-PHTHALIMIDE AND PROCESS THEREFOR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | disclosed |
| US-3998841-A | CHLOROTHIO-N-PHTHALIMIDE AND PROCESS THEREFOR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | disclosed |