Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12088281 | 0.87 | TOP2A (0.53) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12088285 | 0.85 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11674769 | 0.84 | ALDH1A1 (0.45) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12088127 | 0.83 | MAPT (0.46) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11675433 | 0.83 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL8894146 | 0.83 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5950512 | 0.82 | KDM4E (0.52) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12088228 | 0.82 | ALDH1A1 (0.40) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12088101 | 0.82 | SMN1; SMN2 (0.44) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11212433 | 0.82 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120225386-A1 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-09-06 | — | — | US | disclosed |
| US-4074057-A | HYPERLIPEMIA, DIABETES | TAKEDA CHEMICAL CO., LTD. (JA) | 1978-02-14 | — | — | US | disclosed |